Capillary Electrophoresis
Notes:
- charges represent deprotonated silanol groups
+ represent diffuse double layer of positive counterions from buffer (rigid layer and mobile layer of adsorbed ions)
+ charges predominate in the diffuse double layer, and the mobile layer migrates to the neg charged cathode under an applied voltage.
the movement of these solvated cation drag the bulk buffer soln. with them
this is electroosmotic flow
A and B represent neutral molecules (the analyte)
Neutral molecules - no electrophoretic mobility because they have no charge
get swept along with the electroosmotic flow