Slide 12 of 21
Notes:
neutral (can’t be separated by unmodified CE)
wanted to investigate charged CD’s ability to separate neutral species
Chosen because the naphthalene group fits inside the b-CD cavity
Position of OH groups influences steric considerations of CD inclusion
ability to donate H-bonds to O’s on the ring will differ among isomers
expect a variety of binding constants with CD
Therefore, we expect CEKC to separate these neutral compounds