Slide 7 of 21
Notes:
N - number of theoretical plates
alpha - selectivity calculated as the ratio of retention factors
k1’ and k2’ are retention factors of two analytes
to migration time of analytes in the absence of CD
tch migration time of charged CD
If CD were neutral t0 ~ tch and Rs would be 0 no matter what the ks were
If tch >> to the last term approaches 1/k1’
so resolution depends on k’s N and alpha
One way to improve resolution is to give CD more power at swimming upstream.
Increase the difference between t(0) and t(ch).
